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doi: 10.1046/j.1464-5491.2001.00424.x 26 KendallDMRiddleMCRosenstockJZhuangDKimDDFinemanMSet al

Exposure to the drug induced a mitochondria-independent mode of cell death due to the induction of reactive oxygen species (ROS) through erastin-mediated activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase

All patients with confirmed prediabetes begin with structured lifestyle intervention targeting 7% weight loss and 150 minutes per week of moderate activity